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Acute Phase Predictors of Outcome of Low Back Pain (1996 to 2000)
Margareta Nordin (PI), Michael Crane, David Goldsheyder, Manny Halpern, Rudi Hiebert, Sherri Weiser
Studies of duration in low back pain have largely followed patients identified in the subacute phase
(6 weeks to 6 months after onset) or chronic patients. Some inferences have been drawn about predictors
of chronicity from etiology studies on healthy subjects to learn if they subsequently had chronic episodes.
This project is aimed to examine whether a group of patients at high risk of chronicity or recurrence can
be identified during the acute phase of back pain (within 1 month of onset) based on information ascertained
in routine clinical practice, thus filling the gap in current knowledge of this question. The
identification of such a group can lead to studies of the effectiveness of acute phase interventions
in high-risk patients in reducing the overall morbidity and cost of low back pain treatment.
This project is a prospective population-based study of predictors of outcome in low back pain, with an
inception cohort of back pain patients from a population of 50,000 employed individuals. The study will
be conducted in an environment where both union and management jointly support low back pain research.
Data characterizing clinical signs and symptoms upon examination, demographics, attitutes towards work,
expectations of recovery, working conditions, functional status, and pain intensity will be gathered
when an employee first presents at the clinic. The participating medical evaluation facilities see
about 800 low back pain patients each year. Follow-up interviews will be conducted 3 months and 6
months after the initial visit. The relative importance of episode severity, back pain history,
soiciodemographic, attudinal and work-related factors in predicting episode duration, recurrence
of low back pain, and residual functional limitation after one year of follow-up will be examined.
An algorithm for identifying patients at risk of chronicity and recurrence will be developed.
Patterns and predictors of health care utilization and charges for low back pain diagnosis and
te\reatment will also be examined.
This project has been supported by the National Institute of Arthritis and Musculoskeletal and
Skin Diseases (NIAMS) through grant R01-AR44288 for a duration from May 01, 1996 to April 30, 2000.
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